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5''-phosphoribostamycin phosphatase

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Class of enzymes
5′′-phosphoribostamycin phosphatase
Identifiers
EC no.3.1.3.88
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

5′′-phosphoribostamycin phosphatase (EC 3.1.3.88) is an enzyme with systematic name 5′′-phosphoribostamycin phosphohydrolase. This enzyme catalyses the following chemical reaction

5′′-phosphoribostamycin + H2O {\displaystyle \rightleftharpoons } ribostamycin + phosphate

This enzyme is involved in the biosynthesis of several aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin.

References

  1. Kudo F, Fujii T, Kinoshita S, Eguchi T (July 2007). "Unique O-ribosylation in the biosynthesis of butirosin". Bioorganic & Medicinal Chemistry. 15 (13): 4360–8. doi:10.1016/j.bmc.2007.04.040. PMID 17482823.

External links

Hydrolase: esterases (EC 3.1)
3.1.1: Carboxylic
ester hydrolases
3.1.2: Thioesterase
3.1.3: Phosphatase
3.1.4:
Phosphodiesterase
3.1.6: Sulfatase
Nuclease (includes
deoxyribonuclease
and ribonuclease)
3.1.11-16:
Exonuclease
Exodeoxyribonuclease
Exoribonuclease
3.1.21-31:
Endonuclease
Endodeoxyribonuclease
Endoribonuclease
either deoxy- or ribo-    
Enzymes
Activity
Regulation
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