| 7-Methylxanthine demethylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.128 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
7-Methylxanthine demethylase (EC 1.14.13.128) is an enzyme with systematic name 7-methylxanthine:oxygen oxidoreductase (demethylating). This enzyme catalyses the following chemical reaction
- 7-methylxanthine + O2 + NAD(P)H + H xanthine + NAD(P)+ + H2O + formaldehyde
xanthine + NAD(P)+ + H2O + 7-Methylxanthine demethylase is a non-heme iron oxygenase.
References
- Summers RM, Louie TM, Yu CL, Subramanian M (February 2011). "Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source". Microbiology. 157 (Pt 2): 583–92. doi:10.1099/mic.0.043612-0. PMID 20966097.
External links
- 7-methylxanthine+demethylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
| Oxidoreductases: dioxygenases, including steroid hydroxylases (EC 1.14) | |
|---|---|
| 1.14.11: 2-oxoglutarate | |
| 1.14.13: NADH or NADPH | |
| 1.14.14: reduced flavin or flavoprotein | |
| 1.14.15: reduced iron–sulfur protein | |
| 1.14.16: reduced pteridine (BH4 dependent) | |
| 1.14.17: reduced ascorbate | |
| 1.14.18-19: other | |
| 1.14.99 - miscellaneous | |
| Enzymes | |
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| Activity | |
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