8-oxocoformycin reductase | |||||||||
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Identifiers | |||||||||
EC no. | 1.1.1.235 | ||||||||
CAS no. | 114995-16-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 8-oxocoformycin reductase (EC 1.1.1.235) is an enzyme that catalyzes the chemical reaction
- coformycin + NADP 8-oxocoformycin + NADPH + H
Thus, the two substrates of this enzyme are coformycin and NADP, whereas its 3 products are 8-oxocoformycin, NADPH, and H.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is coformycin:NADP 8-oxidoreductase. This enzyme is also called 8-ketodeoxycoformycin reductase.
References
- Hanvey JC, Hawkins ES, Baker DC, Suhadolnik RJ (July 1988). "8-Ketodeoxycoformycin and 8-ketocoformycin as intermediates in the biosynthesis of 2'-deoxycoformycin and coformycin". Biochemistry. 27 (15): 5790–5. doi:10.1021/bi00415a059. PMID 3052586.
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