A2M may refer to:
- The a2 Milk Company, an ASX listed company which sells dairy products, including baby formula
- α2-Macroglobulin, a gene with the ability to inhibit all four classes of proteinases by a unique "trapping" mechanism
- Artificial Mind and Movement, a Canadian games development company
- Ass to mouth, a sexual act
See also
- American Association of Independent Music, abbreviated to A2IM
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