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ABCA10
Identifiers
Aliases	ABCA10, EST698739, ATP binding cassette subfamily A member 10
External IDs	OMIM: 612508; HomoloGene: 122432; GeneCards: ABCA10; OMA:ABCA10 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q24.3 Start 69,147,214 bp End 69,244,846 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial nerve sural nerve left ovary right ovary Achilles tendon right uterine tube lactiferous gland subcutaneous adipose tissue gastric mucosa left uterine tube n/a More reference expression data BioGPS n/a
Gene ontology Molecular function ATP binding nucleotide binding ATPase activity ATPase-coupled transmembrane transporter activity lipid transporter activity Cellular component integral component of membrane intracellular membrane-bounded organelle membrane Biological process lipid transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10349 n/a Ensembl ENSG00000154263 n/a UniProt Q8WWZ4 n/a RefSeq (mRNA) NM_080282 NM_001377321 n/a RefSeq (protein) NP_525021 NP_001364250 n/a Location (UCSC) Chr 17: 69.15 – 69.24 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

ATP binding cassette subfamily A member 10 is a protein that in humans is encoded by the ABCA10 gene.

Function

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. This encoded protein is a member of the ABCA subfamily. Members of the ABCA subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABCA subfamily members on 17q24, but neither the substrate nor the function of this gene is known. .

References

1. ^ GRCh38: Ensembl release 89: ENSG00000154263 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: ATP binding cassette subfamily A member 10". Retrieved 2018-07-27.

Further reading

• Wenzel JJ, Kaminski WE, Piehler A, Heimerl S, Langmann T, Schmitz G (July 2003). "ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter". Biochem. Biophys. Res. Commun. 306 (4): 1089–98. doi:10.1016/s0006-291x(03)01097-0. PMID 12821155.

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