APL is an abbreviation, acronym, or initialism that may refer to:
Science and technology
- 132524 APL, an asteroid
- Abductor pollicis longus muscle, in the human hand
- Acute promyelocytic leukemia, a subtype of acute myelogenous leukemia
- Applied Physics Letters, a physics journal
- Nampula Airport (IATA airport code: APL), in Mozambique
Computers
- .apl, the file extension of the Monkey's Audio metadata file
- AMD Performance Library, renamed Framewave, a computer compiler library
- APL (programming language), an array-based programming language
- APL (codepage), the character set for programming in APL
- Address Prefix List, a DNS record type
- Address (programming language), an early high-level programming language developed in the Soviet Union
- Advanced Physical Layer, an extension of Ethernet 10BASE-T1L for field devices
- Alexa Presentation Language, a language for developing Amazon Alexa skills
- Associative Programming Language, a database query language
Software licences
- Adaptive Public License, an Open Source license from the University of Victoria, Canada
- AROS Public License, a license of AROS Research Operating System
- Arphic Public License, a free font license
Organizations
- APL (shipping company), a Singapore-based container and shipping company
- Aden Protectorate Levies, a militia force for local defense of the Aden Protectorate
- Advanced Production and Loading, a Norwegian marine engineering company formed in 1993
- Afghanistan Premier League, an Afghan Twenty20 cricket league
- Afghan Premier League, a men's football league in Afghanistan
- American Patriot League, a proposed American football spring league
- American Premiere League, a Twenty20 cricket league in the US
- American President Lines, a container transportation and shipping company
- American Protective League, a World War I-era pro-war organization
- Applied Physics Laboratory, at Johns Hopkins University
- Applied Physics Laboratory at the University of Washington
- Association of Pension Lawyers, UK
- Aurora Public Library (disambiguation)
- Australian Professional Leagues, an Australian soccer governing body
- Irish Anti-Partition League, a Northern Ireland political organisation
Other uses
- apl.de.ap (born 1974), pseudonym of Allan Pineda Lindo, Filipino–American musician
- A US Navy hull classification symbol: Barracks craft (APL)
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