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The enzyme acetylajmaline esterase (EC 3.1.1.80, AAE, 2β(R)-17-O-acetylajmalan:acetylesterase, acetylajmalan esterase; systematic name 17-O-acetylajmaline O-acetylhydrolase) catalyses the following reactions:

(1) 17-O-acetylajmaline + H₂O ${\displaystyle \rightleftharpoons }$ ajmaline + acetate

(2) 17-O-acetylnorajmaline + H₂O ${\displaystyle \rightleftharpoons }$ norajmaline + acetate

This plant enzyme mediates the last stages in the biosynthesis of the indole alkaloid ajmaline.

References

1. Polz L, Schübel H, Stöckigt J (April 1987). "Characterization of 2β(R)-17-O-acetylajmalan: acetylesterase--a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid ajmaline". Zeitschrift für Naturforschung C. 42 (4): 333–42. PMID 2955586.
2. Ruppert M, Woll J, Giritch A, Genady E, Ma X, Stöckigt J (November 2005). "Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system". Planta. 222 (5): 888–98. doi:10.1007/s00425-005-0031-0. PMID 16133216.

External links

• Acetylajmaline+esterase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 3.1.1