| Acral necrosis | |
|---|---|
 | |
| A hand with acral gangrene due to plague | |
| Differential diagnosis | bubonic plague |
Acral necrosis is a symptom common in bubonic plague. The striking black discoloration of skin and tissue, primarily on the extremities ("acral"), is commonly thought to have given rise to the name "Black Death," associated both with the disease and the pandemic which occurred in the 14th century. The term in fact came from the figural sense of "black", that is ghastly, lugubrious or dreadful.
Acral necrosis may be a symptom of other diseases too. It also has been observed as an adverse event related to a medical treatment.
References
- Antosia, Robert; Cahill, John D. (2006). Handbook of Bioterrorism and Disaster Medicine. Springer Science & Business Media. p. 110. ISBN 9780387328041. Retrieved 8 November 2017.
- Roy, Michael J. (2003). Physician's Guide to Terrorist Attack. Springer Science & Business Media. p. 92. ISBN 9781592596638. Retrieved 8 November 2017.
- Khaddour, Karam; Singh, Veerpal; Shayuk, Maryna (2019-05-14). "Acral vascular necrosis associated with immune-check point inhibitors: case report with literature review". BMC Cancer. 19 (1): 449. doi:10.1186/s12885-019-5661-x. ISSN 1471-2407. PMC 6518656. PMID 31088420.
- Reiser, M.; Bruns, C.; Hartmann, P.; Salzberger, B.; Diehl, V.; Fätkenheuer, G. (January 1998). "Raynaud's phenomenon and acral necrosis after chemotherapy for AIDS-related Kaposi's sarcoma". European Journal of Clinical Microbiology & Infectious Diseases. 17 (1): 58–60. doi:10.1007/BF01584368. ISSN 0934-9723. PMID 9512187. S2CID 20332412.
External links
- eMedicine site: Description and graphic photographs
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