Agios Spyridonas (Greek meaning Saint Spyridon) may refer to the following places in Greece:
- Agios Spyridonas, Boeotia, a village in Boeotia
- Agios Spyridonas, Corfu, a beach and nature reserve in Corfu
- Agios Spyridonas, Phocis, a village in Phocis
- Agios Spyridonas, Pieria, a village in Pieria
- Agios Spiridonas (Limassol), a district of the Municipality of Limassol
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