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Sayin attended Carlsbad High School in Carlsbad, California. He did not become the starting quarterback for the Lancers until his junior year in 2019. In 2019, Sayin led the Lancers to a 10–2 (6–0) record and an Avocado League championship. He also threw for 2,349 yards, 24 touchdowns, and eight interceptions. Due to the COVID-19 pandemic, the 2020 season was cut short to only five games. Sayin led the Lancers to another Avocado League championship with a 5–0 (4–0) record. In five games, Sayin threw for 962 yards and 13 touchdowns. On September 6, 2020, Sayin committed to the University of Pennsylvania.
Sayin started the 2021 season as the backup to senior, John Quinnelly. Sayin saw his first action against the Yale Bulldogs. He finished 12-for-28, 114 yards, and two touchdowns. Sayin's final game of the season was against Princeton, passing for 255 yards, a touchdown, and two interceptions. Starting the last five games of the season, Sayin passed for 920 yards on 163 attempts to 88 completions, and five touchdowns to seven interceptions.
2022 season
Sayin was named the starter going into the 2022 season. In the first game of the season, Sayin passed for 289 yards and two touchdowns in a 25–14 victory. Against Dartmouth, Sayin and the Quakers went to double-overtime where he threw for 204 yards and a touchdown in 23–17 win. Against Georgetown, Sayin accounted for five total touchdowns, which was the most by a Quaker since 2010, in a 59–28 win. Against No. 22 Princeton, Sayin led a fourth-quarter comeback to win, 20–19. During the game, he completed 38 passes, second-most in program history, for 261 yards and two touchdowns. He would win Ivy League Offensive Player of the Week for his efforts. Sayin finished the season with 253 completions (1st Ivy), 2,344 yards (2nd), and 18 touchdowns (T–1st). His passing yardage was fifth most in program history and the most since Alek Torgersen had 2,689 yards in 2014. Sayin was named All-Ivy Honorable Mention at the end of the season. He was also named to the College Sports Communicators Academic All-District Team.
Sayin's younger brother, Julian, is also a college football quarterback and a 2024 college football prospect who plays for the Ohio State Buckeyes. His older sister, Bailey, played soccer at the University of Chicago.