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Alan Garen was an American geneticist who co-discovered suppressor mutations for tRNA. The Garen lab also showed that certain triplet codons (5'-UAG, 5'-UAA, and 5'-UGA) failed to bind amino acids. Thus, the Garen lab and Brenner labs are both credited with discovery of the stop codons of the genetic code.

Garen was a professor at Yale University between 1963 and 2021. He was a member of the National Academy of Sciences and the American Academy of Arts and Sciences.

References

1. Weigert M, Galluci E, Lanka E, Garen A (1966). "Characteristics of the genetic code in vivo". Cold Spring Harb Symp Quant Biol. 31: 145–150. doi:10.1101/sqb.1966.031.01.022. PMID 4866371.
2. Stretton AO, Kaplan S, Brenner S (1966). "Nonsense codons". Cold Spring Harb Symp Quant Biol. 31: 173–179. doi:10.1101/sqb.1966.031.01.025. PMID 5237189.
3. "MB&B bids farewell to Tom Pollard and Alan Garen | Molecular Biophysics and Biochemistry".

External links

• Garen's webpage at Yale's Dept. of Molecular Biophysics and Biochemistry
• Academic genealogy of Alan Garen

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• Members of the United States National Academy of Sciences
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