Alexander of Macedon may refer to:
- Alexander I of Macedon (died 454 BC), ruled from 498 to 454 BC
- Alexander II of Macedon (died 368 BC), ruled from 370 to 368 BC
- Alexander III of Macedon (356–323 BC), or Alexander the Great, ruled from 336 to 323 BC
- Alexander IV of Macedon (323–310 BC), ruled as a child-king from birth to death
- Alexander V of Macedon (died 294 BC), ruled with his brother Antipater from c. 297–294 BC
- Alexander (son of Perseus), a child in the 160s
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