Alfredo Di Stéfano (1926–2014) was an Argentine-Spanish footballer and coach.
Alfredo Di Stéfano may also refer to:
- Alfredo di Stéfano Stadium, the home ground of Real Madrid Castilla
- Alfredo Di Stéfano Trophy (testimonial match), a testimonial match for Alfredo Di Stéfano in 1967
- Trofeo Alfredo Di Stéfano, a trophy awarded by Spanish sports newspaper Marca to the best footballer of La Liga
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