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In the 20th season premiere, Roger's origin story is told, taking place in 1947 setting up the Roswell Incident, revealing Roger's passion for personas and how Avery Bullock's father (Avery Bullock Senior) was on the search for the alien way before him.

Roger's new professor persona teaches at Hayley's college, and asks Hayley to help him write a book about his experiences. Meanwhile, Jeff writes a rap to stop the Bazooka Sharks from leaving Langley Falls.

Steve and Principal Lewis try to escape Pearl Bailey High School from three convicts who're connected to the school. Meanwhile, the Smiths befriend a baby giraffe that has escaped a zoo.

Klaus buys a comb from an estate sale that harbors a wraith whose presence threatens Klaus' friendship with Jeff. Meanwhile, Stan gets his jaw wired shut after getting punched in the face.

Fed up with the rest of the family criticizing his decision-making, Jeff decides to prove them wrong by becoming a legging salesman.

Stan discovers some old love poems in Francine's closet that come from his workplace. It turns out to be a printer powered by the romantic lobe from his brain, which he decides to take home, but things soon get out of hand when it gains sentience.

Hayley tries to rid herself of her inner voice with help from Dr. Penguin (Roger's therapist persona) after it ruins her girls' night, but her attempts only make the voice's presence even larger.

Francine insists on helping Steve with his class project, while Stan finally gets around to fixing the broken shingle on the house's roof. Meanwhile, the other Smiths head out to return Gallagher's mallet.

Stan is swayed to get some work done to maintain his "peak," but it turns out to be a trap by an old rival he didn't know he had. Meanwhile, Roger goes on a wild goose chase in pursuit of an apple he bought at the farmer's market.

When Stan goes too far to keep his work friend away from Francine, she is forced to save her new friend by going inside Stan's body. Meanwhile, Jeff and Hayley live the good life after finding a Lamborghini tire.

Hayley makes Jeff get a friend to add some mystery to their relationship but gets more mystery than she bargained for when she discovers that Jeff's new friend may be a serial killer.

When the Smiths get new next-door neighbors, Francine hits it off with the wife of the family, while the others plot to drive them away. Meanwhile, Roger's latest persona sees him acting as the kite of a neglected boy.

Francine quickly rises to fame after her homemade pottery is discovered by a famous art dealer, but when the fame becomes too much, Francine checks herself into a mental hospital.

Hayley tries to find Steve so they can go to a Shaggy concert, but the endeavor takes her and Steve on a multiversal adventure.

Stan ends up missing and Francine, Jeff, Steve, Klaus and Hayley (dressed as Daphne, Shaggy, Velma, Scooby, and Fred from Scooby-Doo) try to find where he's gone.

Roger seeks out a mythical giant whom he believes is responsible for the windy weather, borrowing a CIA yacht to investigate and bringing the family along for a makeshift vacation. Unable to trust Klaus to housesit while they're away, the Smiths hire Dick to keep an eye on him, unaware that he is plotting to squat in their home forever.

When the Smiths' dysfunctional antics are reported to Social Services, the family must clean up their act for one evening to impress the social worker, but various complications get in the way.

Stan and Roger feel that they haven't made an impact on the world and plan to rectify this by pitching a new TV show and revealing Roger's secret. Meanwhile, picking up from where the B-plot of "Mean Francine" left off, Jeff tries to find a new hat after losing his usual one.

In order to get into a cool kid's party, Steve and Snot hunt down a rare keg of Four Loko beer, but their usage of Roger's disguises to appear as adults adds further complications to their quest.

When Francine laments the fact that she can't hide her thoughts well, Roger tries to rectify this by training her in professional poker.

Jealous of the money she's making, Francine joins Hayley in selling pharmaceuticals harvested from armadillos. Meanwhile, Roger helps Stan perfect his sad face in order to avoid losing the house.

After Steve outclasses him on Christmas with the presents he gifts the family, Stan goes to great lengths to reclaim his title as the "King of Presents."

• Stan Smith
• Francine Smith
• Steve Smith
• Hayley Smith
• Roger
• Klaus

• Animation Throwdown: The Quest for Cards
• Warped Kart Racers
• Hayley Sings
• Animation Domination