Androgen-dependent condition | |
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Specialty | Endocrinology |
An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.
Known androgen-dependent conditions include acne, seborrhea, androgenic alopecia, hirsutism, hidradenitis suppurativa, precocious puberty in boys, hypersexuality, paraphilias, benign prostatic hyperplasia (BPH), prostate cancer, and hyperandrogenism in women such as in polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia (CAH), and androgen-secreting tumors (gonadal or adrenal tumor).
Such conditions may be treated with drugs with antiandrogen actions, including androgen receptor antagonists such as cyproterone acetate, spironolactone, and bicalutamide, 5α-reductase inhibitors such as finasteride and dutasteride, CYP17A1 inhibitors such as abiraterone acetate, gonadotropin-releasing hormone (GnRH) analogues such as leuprorelin and cetrorelix, and/or other antigonadotropins such as megestrol acetate and medroxyprogesterone acetate.
See also
- Androgen deprivation therapy
- Androgen insensitivity syndrome
- Estrogen-dependent condition
- Spinal bulbar muscular atrophy
References
- Joseph E. Pizzorno; Michael T. Murray (2013). Textbook of Natural Medicine. Elsevier Health Sciences. pp. 1157–. ISBN 978-1-4377-2333-5.
- Steven B. Hoath; Howard I. Maibach (18 April 2003). Neonatal Skin: Structure and Function. CRC Press. pp. 67–. ISBN 978-0-8247-0887-0.
- Mariagrazia Stracquadanio; Lilliana Ciotta (20 April 2015). Metabolic Aspects of PCOS: Treatment With Insulin Sensitizers. Springer International Publishing. pp. 25–. ISBN 978-3-319-16760-2.
- Krishna; Usha R. (1 March 2000). Adolescence. Orient Blackswan. pp. 124–. ISBN 978-81-250-1794-3.
- Mark G. Lebwohl; Warren R. Heymann; John Berth-Jones; Ian Coulson (19 September 2013). Treatment of Skin Disease: Comprehensive Therapeutic Strategies. Elsevier Health Sciences UK. pp. 36–. ISBN 978-0-7020-5236-1.
- Wilma F. Bergfeld (22 February 1996). A Woman Doctor's Guide to Skin Care: Essential Facts and Information on Keeping Skin Healthy. Hyperion. ISBN 978-0-7868-8100-0.
- Sarah Bekaert (2007). Women's Health: A Practical Guide for Healthcare Professionals. Radcliffe Publishing. pp. 128–. ISBN 978-1-84619-029-2.
- Ora Hirsch Pescovitz; Erica A. Eugster (2004). Pediatric Endocrinology: Mechanisms, Manifestations, and Management. Lippincott Williams & Wilkins. pp. 328–. ISBN 978-0-7817-4059-3.
- Newsletter. The Academy. 1986.
- Adrian Raine (2006). Crime and Schizophrenia: Causes and Cures. Nova Publishers. pp. 290–. ISBN 978-1-59454-609-9.
- Christopher R. Chapple; William D. Steers (10 May 2011). Practical Urology: Essential Principles and Practice: Essential Principles and Practice. Springer Science & Business Media. pp. 361–. ISBN 978-1-84882-034-0.
- P. J. Bentley (1980). Endocrine Pharmacology: Physiological Basis and Therapeutic Applications. CUP Archive. pp. 321–. ISBN 978-0-521-22673-8.
- Raphael Rubin; David S. Strayer; Emanuel Rubin; Jay M. McDonald (2008). Rubin's Pathology: Clinicopathologic Foundations of Medicine. Lippincott Williams & Wilkins. pp. 816–. ISBN 978-0-7817-9516-6.
- Andrea Dunaif; R. Jeffrey Chang; Stephen Franks; Richard S. Legro (12 January 2008). Polycystic Ovary Syndrome: Current Controversies, from the Ovary to the Pancreas. Springer Science & Business Media. pp. 222–. ISBN 978-1-59745-108-6.
- Kenneth L. Becker (2001). Principles and Practice of Endocrinology and Metabolism. Lippincott Williams & Wilkins. pp. 1195–. ISBN 978-0-7817-1750-2.
- Annual Reports in Medicinal Chemistry. Academic Press. 3 October 1994. pp. 1994–. ISBN 978-0-08-058373-0.
Further reading
- Shukla, G. C.; Plaga, A. R.; Shankar, E.; Gupta, S. (2016). "Androgen receptor-related diseases: what do we know?". Andrology. 4 (3): 366–381. doi:10.1111/andr.12167. ISSN 2047-2919. PMID 26991422.
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