Anethole trithione - Misplaced Pages

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Pharmaceutical compound

Anethole trithione
Clinical data


ATC code	A16AX02 (WHO)
Identifiers
IUPAC name 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione
CAS Number	532-11-6
PubChem CID	2194
DrugBank	DB13853
ChemSpider	2109
UNII	QUY32964DJ
KEGG	D01584
ChEMBL	ChEMBL178862
CompTox Dashboard (EPA)	DTXSID9046651
ECHA InfoCard	100.007.754
Chemical and physical data
Formula	C₁₀H₈OS₃
Molar mass	240.35 g·mol
3D model (JSmol)	Interactive image
SMILES S=C\2SS/C(c1ccc(OC)cc1)=C/2
InChI InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3 Key:KYLIZBIRMBGUOP-UHFFFAOYSA-N
(verify)

Anethole trithione, anetholtrithione, or anetholtrithion (JAN) is a drug used in the treatment of dry mouth. It is listed in the U.S. National Cancer Institute's Dictionary of Cancer Terms as being studied in the treatment of cancer. Anethole trithione is an organosulfur compound, specifically, a dithiole-thione derivative.

Brand names

Felviten
Halpen
Hepasulfol - Franco-Indian Pharmaceuticals
Heporal
Mucinol - Sanofi-Aventis
Sialor - Paladin Laboratories; Pharmascience; Solvay; Zuoz Pharma
Sonicur - Solvay
Sulfarlem - Solvay; Aguettant; Edward Keller; Sanofi-Aventis
Sulfarlem S - EG Labo
Tiopropen
Tiotrifar

References

Anetholtrithione entry in the public domain NCI Dictionary of Cancer Terms. Retrieved September 13, 2008.
Christen MO (1995). "Anethole dithiolethione: Biochemical considerations". Biothiols Part B: Glutathione and Thioredoxin: Thiols in Signal Transduction and Gene Regulation. Methods in Enzymology. Vol. 252. pp. 316–23. doi:10.1016/0076-6879(95)52034-1. ISBN 9780121821531. PMID 7476368.

v t e Other alimentary tract and metabolism products (A16)
Amino acids and derivatives	Ademetionine Betaine Carglumic acid Glutamine Levocarnitine Mercaptamine Metreleptin
Enzymes	Amino acids: phenylalanine ammonia-lyase (Pegvaliase) Carbohydrate metabolism: sucrase (Sacrosidase) alpha-glucosidase (Alglucosidase alfa, Avalglucosidase alfa, Cipaglucosidase alfa) Glycolipid/sphingolipid: glucocerebrosidase (Alglucerase Imiglucerase Taliglucerase alfa Velaglucerase alfa) alpha-galactosidase (Agalsidase alfa Agalsidase beta Pegunigalsidase alfa) Glycosaminoglycan: iduronidase (Laronidase) arylsulfatase B (Galsulfase) iduronate-2-sulfatase (Idursulfase) idursulfase beta Lipid: lysosomal lipase (Sebelipase alfa) Phosphate: Asfotase alfa atidarsagene autotemcel cerliponase alfa eladocagene exuparvovec elosulfase alfa olipudase alfa pabinafusp alfa pegzilarginase vestronidase alfa
Other	Anethole trithione Eliglustat Givosiran Glycerol phenylbutyrate Leriglitazone Lumasiran Miglustat Nedosiran Nitisinone Sapropterin Sepiapterin Sodium benzoate (+sodium phenylacetate) Sodium phenylbutyrate Teduglutide Trientine Tioctic acid Triheptanoin Uridine triacetate Velmanase alfa Zinc acetate

Other alimentary tract and metabolism products (A16)

Amino acids and derivatives

Enzymes

Amino acids: phenylalanine ammonia-lyase (Pegvaliase)

Glycosaminoglycan: iduronidase (Laronidase)
arylsulfatase B (Galsulfase)
iduronate-2-sulfatase (Idursulfase)
idursulfase beta

Lipid: lysosomal lipase (Sebelipase alfa)

Phosphate: Asfotase alfa

Other

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Categories:

Brand names

See also

References