Angela Casini | |
---|---|
Alma mater | University of Florence |
Awards | European Medal for Bio-Inorganic Chemistry |
Scientific career | |
Institutions | Technical University of Munich University of Groningen |
Angela Casini is a medicinal and inorganic chemist who works on metal-based compounds as therapeutic agents. She was awarded the 2012 European Medal for Bio-Inorganic Chemistry and made the 2019 American Chemical Society Inorganic Lecturer.
Early life and education
She earned her PhD in chemical sciences at the University of Florence in 2004. She was a postdoctoral fellow at the University of Pisa, where she worked on the mechanisms by which metal-complexes that are used as anti-cancer agents activate. She used both spectroscopy, including mass spectrometry imaging, and molecular biology.
Research and career
Angela Casini joined the École Polytechnique Fédérale de Lausanne as a Principal Investigator in 2008. She moved to the University of Groningen in 2011, where she was made a Rosalind Franklin Fellow. She was made a Chair of Medicinal Chemistry at Cardiff University in 2015, and has served as Director of Postgraduate Teaching from 2018. She spent 2016 as a visiting professor at the Technical University of Munich.
Awards and honours
Her awards and honours include;
- 2012 European Medal for Bio-Inorganic Chemistry
- 2014 Gordon Research Conference Early Career Investigator
- 2014 Thomson Reuters World's Most Influential Scientific Mind
- 2016 Elected to the Young Academy of Europe
- 2018 Burghausen Diamond of Chemistry Award
- 2019 American Chemical Society Inorganic Lectureship Award
Selected publications
Her publications include;
- Casini, Angela (2003). "Carbonic anhydrase inhibitors". Medicinal Research Reviews. 23 (2): 146–189. doi:10.1002/med.10025. PMID 12500287. S2CID 90349277.
- Casini, Angela (2004). "Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH". FEBS Letters. 577 (3): 439–445. doi:10.1016/j.febslet.2004.10.043. PMID 15556624. S2CID 37646843.
- Casini, Angela (2004). "Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition". Journal of Medicinal Chemistry. 47 (3): 550–557. doi:10.1021/jm030912m. PMID 14736236.
Casini serves on the editorial board of the Journal of Biological Inorganic Chemistry and the Journal of Inorganic Biochemistry.
References
- ^ Gabbiani, Chiara; Casini, Angela; Messori, Luigi (2007-03-01). "Gold(III) compounds as anticancer drugs". Gold Bulletin. 40 (1): 73–81. doi:10.1007/BF03215296. ISSN 2190-7579.
- Medicinal, Professor Angela Casini Chair of; Chemistry, Bioinorganic. "Professor Angela Casini - People". Cardiff University. Retrieved 2019-08-26.
- Casini, Angela; Woods, Benjamin; Wenzel, Margot (2017-12-18). "The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications". Inorganic Chemistry. 56 (24): 14715–14729. doi:10.1021/acs.inorgchem.7b02599. ISSN 0020-1669. PMID 29172467.
- "Institute for Advanced Study (IAS): Casini, Angela". www.ias.tum.de. Retrieved 2019-08-26.
- "The School of Chemistry welcomes new staff member Professor Angela Casini". Cardiff University. Retrieved 2019-08-26.
- "EuroBIC". www.bioinorganic-chemistry.org. Retrieved 2019-08-26.
- "2014 Metals in Medicine Conference GRC". www.grc.org. Retrieved 2019-08-26.
- "Angela Casini". metallomics2017.univie.ac.at. Retrieved 2019-08-26.
- "Angela Casini – Young Academy of Europe". 18 December 2016. Retrieved 2019-08-26.
- "Burghausen Chemistry Award for Angela Casini". www.tum.de. Retrieved 2019-08-26.
- "Burghausen Chemistry Award for Angela Casini". www.tum.de. Retrieved 2019-08-26.
- "Angela Casini Receives 2019 Inorganic Chemistry Lectureship Award". ACS Axial. 2019-03-12. Retrieved 2019-08-26.
- Medicinal, Professor Angela Casini Chair of; Chemistry, Bioinorganic; PGT, Director of. "Prof Angela Casini wins 2019 Inorganic Chemistry Lectureship Award". Cardiff University. Retrieved 2019-08-26.