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Apocynaceae alkaloids are natural products found in the plant family of the dogbane family (Apocynaceae).

Occurrence

The alkaloid tabernanthin is found in Tabernaemontana laurifolia. The alkaloids voacangin and voacristin were isolated from Voacanga africana.

Representatives

Representatives include tabernanthine, voacangine and voacristine.

• (-)-Voacangine
• (-)-Voacristine
• Tabernanthine

Uses

Plant parts of Voacanga africana are utilized by African natives for various purposes, including as hallucinogens, in cultic ceremonies, and as aphrodisiacs.

Ethnomedicinal use

A decoction made from the stem or root bark is employed for the treatment of mental disorders and as an analgesic. The sap is applied to cavities in teeth. In southeastern Nigeria, Voacanga africana is an integral part of numerous healing rituals.

References

1. Entry on Apocynaceen-Alkaloide. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.Error in template * unknown parameter name (Template:RömppOnline): "Abruf"
2. M.Hesse (1968), Indolalkaloide, Berlin Heidelberg: Springer-Verlag, p. 30, ISBN 978-3-540-04194-8
3. U. Renner (1957), "Voacamidin und Voacristin, zwei neue Alkaloide aus Voacanga africana Stapf", Experientia, vol. 13, pp. 468–469, doi:10.1007/BF02159399
4. Zetler, G.; Lenschow, E.; Prenger-Berninghoff, W. (1968), "Die Wirkung von 11 Indol-Alkaloiden auf das Meerschweinchen-Herz in vivo und in vitro, verglichen mit 2 synthetischen Azepinoindolen, Chinidin und Quindonium.", Naunyn-Schmiedebergs Archiv für Pharmakologie und experimentelle Pathologie, vol. 260, pp. 26–49, doi:10.1007/BF00545005
5. Robert F. Raffauf & M. B. Flagler (1960), "Alkaloids of the Apocynaceae", Economic Botany pages, vol. 14, pp. 37–55, doi:10.1007/BF02859365
6. Lexicon of Medicinal Plants and Drugs, Spektrum Akademischer Verlag 1999.
7. M. Iwu, Maurice (2014), Handbook of African Medicinal Plants (2. ed.), CRC Press, ISBN 978-1-46657-198-3

• Alkaloids