Arnold Caplan (1942–2024) was a scientist and professor at Case Western Reserve University known for being the father of mesenchymal stem cells (MSCs). His initial work focused on the “Mesengenic process” whereby MSC’s could be preferentially differentiated into the numerous tissues of the mesodermal lineage
Career
He joined Case Western in 1969.
He founded Osiris Therapeutics in 1992.
He has said "by calling them “Mesenchymal Stem Cells,” we are misrepresenting what the cells’ true functions are in the body; instead, he proposes that these cells be renamed “Medicinal Signaling Cells,” to better reflect their main functions in the body: an intelligent source of therapeutic signals for the body to repair and regenerate."
References
- "Remembering Arnold Caplan: Father Of Mesenchymal Stem Cells". Stem Cell Institute Panama. January 22, 2024.
- Grande, Daniel A. (17 January 2024). "In Memoriam: Arnold Caplan, PhD † (1942-2024)". International Cartilage Regeneration & Joint Preservation Society.
- Smith, Brianna (January 17, 2024). "Faculty member Arnold Caplan passes away". Case Western Reserve University Daily.
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