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Asparagusate reductase (EC 1.8.1.11) is an enzyme that catalyzes the chemical reaction

3-mercapto-2-mercaptomethylpropanoate + NAD ${\displaystyle \rightleftharpoons }$ asparagusate + NADH + H

Thus, the two substrates of this enzyme are 3-mercapto-2-mercaptomethylpropanoate and nicotinamide adenine dinucleotide ion, whereas its 3 products are asparagusate, nicotinamide adenine dinucleotide, and hydrogen ion.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase. Other names in common use include asparagusate dehydrogenase, asparagusic dehydrogenase, asparagusate reductase (NADH2), and NADH2:asparagusate oxidoreductase.

References

• Yanagawa H, Egami F (1975). "Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria". Biochim. Biophys. Acta. 384 (2): 342–52. doi:10.1016/0005-2744(75)90035-2. PMID 1125255.
• Yanagawa H, Egami F (1976). "Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria. Physical, chemical, and enzymatic properties". J. Biol. Chem. 251 (12): 3637–44. PMID 180003.

• Biology

• EC 1.8.1
• NADH-dependent enzymes
• Enzymes of unknown structure