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BAIAP3

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Protein-coding gene in the species Homo sapiens
BAIAP3
Identifiers
AliasesBAIAP3, BAP3, BAI1 associated protein 3
External IDsOMIM: 604009; MGI: 2685783; HomoloGene: 20844; GeneCards: BAIAP3; OMA:BAIAP3 - orthologs
Gene location (Human)
Chromosome 16 (human)
Chr.Chromosome 16 (human)
Chromosome 16 (human)Genomic location for BAIAP3Genomic location for BAIAP3
Band16p13.3Start1,333,638 bp
End1,349,441 bp
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)
Chromosome 17 (mouse)Genomic location for BAIAP3Genomic location for BAIAP3
Band17|17 A3.3Start25,461,633 bp
End25,475,338 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • anterior pituitary

  • right frontal lobe

  • Brodmann area 9

  • cingulate gyrus

  • anterior cingulate cortex

  • Hypothalamus

  • Amygdala

  • olfactory zone of nasal mucosa

  • prefrontal cortex
Top expressed in
  • arcuate nucleus

  • ventromedial nucleus

  • dorsomedial hypothalamic nucleus

  • median eminence

  • paraventricular nucleus of hypothalamus

  • suprachiasmatic nucleus

  • lateral hypothalamus

  • nucleus of stria terminalis

  • central gray substance of midbrain

  • ventral tegmental area
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

8938

545192

Ensembl

ENSG00000007516

ENSMUSG00000047507

UniProt

O94812

Q80TT2

RefSeq (mRNA)
NM_001199096
NM_001199097
NM_001199098
NM_001199099
NM_001286464

NM_003933

NM_001163270

RefSeq (protein)
NP_001186025
NP_001186026
NP_001186027
NP_001186028
NP_001273393

NP_003924

n/a

Location (UCSC)Chr 16: 1.33 – 1.35 MbChr 17: 25.46 – 25.48 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

BAI1-associated protein 3 is a protein that in humans is encoded by the BAIAP3 gene.

BAIAP3 was identified as a protein-binding partner of BAI1. BAI1 is a p53-target gene that encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. BAIAP3 interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. BAIAP3 also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions.

Interactions

BAIAP3 has been shown to interact with Brain-specific angiogenesis inhibitor 1.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000007516Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000047507Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Shiratsuchi T, Oda K, Nishimori H, Suzuki M, Takahashi E, Tokino T, Nakamura Y (Nov 1998). "Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1". Biochem Biophys Res Commun. 251 (1): 158–65. doi:10.1006/bbrc.1998.9408. PMID 9790924.
  6. ^ "Entrez Gene: BAIAP3 BAI1-associated protein 3".

External links

Further reading


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