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BET1L
Identifiers
Aliases	BET1L, BET1L1, GOLIM3, GS15, HSPC197, Bet1 golgi vesicular membrane trafficking protein like
External IDs	OMIM: 615417; MGI: 1913128; HomoloGene: 10293; GeneCards: BET1L; OMA:BET1L - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.5 Start 167,784 bp End 207,399 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 F4 Start 140,433,307 bp End 140,437,490 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas anterior pituitary left ovary right coronary artery Descending thoracic aorta body of stomach gastric mucosa canal of the cervix ascending aorta stromal cell of endometrium Top expressed in dentate gyrus of hippocampal formation granule cell molar parotid gland granulocyte seminal vesicula calvaria spermatocyte motor neuron crypt of lieberkuhn of small intestine decidua More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SNAP receptor activity Cellular component integral component of membrane Golgi membrane endosome Golgi apparatus SNARE complex membrane cytosol Golgi trans cisterna Golgi stack integral component of Golgi membrane Biological process protein transport endoplasmic reticulum to Golgi vesicle-mediated transport retrograde transport, endosome to Golgi regulation of retrograde vesicle-mediated transport, Golgi to ER membrane fusion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51272 54399 Ensembl ENSG00000177951 ENSMUSG00000025484 UniProt Q9NYM9 O35153 RefSeq (mRNA) NM_016526 NM_001098787 NM_016465 NM_018742 RefSeq (protein) NP_001092257 NP_057610 NP_061212 Location (UCSC) Chr 11: 0.17 – 0.21 Mb Chr 7: 140.43 – 140.44 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

BET1-like protein is a protein that in humans is encoded by the BET1L gene.

Interactions

BET1L has been shown to interact with:

• GOSR1,
• STX5, and
• YKT6.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000177951 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000025484 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Xu Y, Wong SH, Zhang T, Subramaniam VN, Hong W (Sep 1997). "GS15, a 15-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) homologous to rbet1". J Biol Chem. 272 (32): 20162–6. doi:10.1074/jbc.272.32.20162. PMID 9242691.
6. Oka T, Ungar D, Hughson FM, Krieger M (Apr 2004). "The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins". Mol Biol Cell. 15 (5): 2423–35. doi:10.1091/mbc.E03-09-0699. PMC 404034. PMID 15004235.
7. "Entrez Gene: BET1L blocked early in transport 1 homolog (S. cerevisiae)-like".
8. ^ Shorter J, Beard MB, Seemann J, Dirac-Svejstrup AB, Warren G (Apr 2002). "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115". J. Cell Biol. 157 (1): 45–62. doi:10.1083/jcb.200112127. PMC 2173270. PMID 11927603.
9. ^ Xu Y, Martin S, James DE, Hong W (Oct 2002). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC 129961. PMID 12388752.

External links

• Human BET1L genome location and BET1L gene details page in the UCSC Genome Browser.

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. Bibcode:2001Sci...291.1304V. doi:10.1126/science.1058040. PMID 11181995.
• Zhang T, Hong W (2001). "Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport". J. Biol. Chem. 276 (29): 27480–7. doi:10.1074/jbc.M102786200. PMID 11323436.
• Shorter J, Beard MB, Seemann J, et al. (2002). "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115". J. Cell Biol. 157 (1): 45–62. doi:10.1083/jcb.200112127. PMC 2173270. PMID 11927603.
• Xu Y, Martin S, James DE, Hong W (2003). "GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus". Mol. Biol. Cell. 13 (10): 3493–507. doi:10.1091/mbc.E02-01-0004. PMC 129961. PMID 12388752.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Tai G, Lu L, Wang TL, et al. (2005). "Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network". Mol. Biol. Cell. 15 (9): 4011–22. doi:10.1091/mbc.E03-12-0876. PMC 515336. PMID 15215310.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

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