Barbier is a French surname. Notable people with the surname include:
- Antoine Alexandre Barbier (1765–1825), French librarian
- Carl Barbier (born 1944), U.S. Federal Judge, Eastern District of Louisiana
- Charles Barbier (1767–1841), French inventor of alternative writing methods
- Charles Barbier de Meynard (1826–1908), French historian and orientalist
- Christophe Barbier (born 1967), French journalist
- Edmond Jean François Barbier (1689–1771), French jurisconsult
- Darren Barbier (born 1960), American college football coach
- Gabriel Barbier-Mueller, Swiss CEO of Harwood International
- George Barbier (illustrator) (1882–1932), French illustrator
- George Barbier (actor) (1864–1945), American actor
- Henri Auguste Barbier (1805–1882), French dramatist and poet
- Jean-François Barbier (1754–1828), French general during the French Revolutionary Wars and Napoleonic Wars
- Joannès Barbier (1854-1909), French photographer in colonial Africa
- Joseph-Émile Barbier (1839–1889), French astronomer and mathematician
- Leonid Barbier (1937–2023), Soviet swimmer
- Louis Barbier (1593–1670), French bishop
- Philippe Barbier (1848–1922), French organic chemist
- Pierre Barbier (born 1997), French racing cyclist
- René Barbier (1891–1966), French fencer
- Rudy Barbier (born 1992), French racing cyclist
- Sal Barbier (born 1969), American skateboarder and footwear designer
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