Barykin, feminine: Barykina (Russian: Барыкин, Барыкина) is a Russian-language surname. Notable people with the surname include:
- Alexander Barykin (1952-2011), Soviet and Russian singer and songwriter
- Mariya Barykina (born 1973), Russian ice hockey player
- Vladimir Barykin (1879-1939), Russian microbiologist and epidemiologist
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