Benigni is a surname. Notable people with the surname include:
- Roberto Benigni (born 1952), Italian actor, comedian, screenwriter and director
- Umberto Benigni (1862–1934), Italian Catholic priest and Church historian
- Mark D. Benigni (born 1972), American politician; former mayor of Meriden, Connecticut
See also
- 21662 Benigni (1999 RC), a main-belt asteroid
- Benign
- Benigno (disambiguation)
- Benignus (disambiguation)
- Benini
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