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Bessarion was a Byzantine Greek scholar who became a Roman Catholic cardinal and Latin Patriarch of Constantinople.

Bessarion can also refer to:

• Bessarion of Egypt, (4th century – 5th century), Egyptian Christian monk
• Bessarion II of Larissa (1489/90–1540), Bishop of Larissa
• Bessarion station, the Toronto Transit Commission subway station
• Bessarion (crater), a lunar crater
• Bessarion (designer), Georgian fashion designer

• Disambiguation pages