Main article: Boxing at the 2010 South American Games
The Men's 54 kg event at the 2010 South American Games had its quarterfinals held on March 23, the semifinals on March 25 and the final on March 27.
Medalists
| Gold | Silver | Bronze |
Oscar Negrete Colombia
|
Alberto Melián Argentina
|
Yohandry Campos VenezuelaCesar Dahua Tuisima  Peru
|
Results
| Quarterfinals | Semifinals | Final | |||||||||
| Alberto Melián (ARG)
| 5 | ||||||||||
| Cesar Dahua Tuisima (PER)
| 2 | ||||||||||
| Alberto Melián (ARG)
| 1 | ||||||||||
| Oscar Negrete (COL)
| 10 | ||||||||||
| Yohandry Campos (VEN)
| RSC | ||||||||||
 Bernardo Santura Paco (BOL)
| |||||||||||
| Yohandry Campos (VEN)
| 1 | ||||||||||
| Oscar Negrete (COL)
| 9 | ||||||||||
| Oscar Negrete (COL)
| 9 | ||||||||||
 Jean Carvalho (BRA)
| 2 | ||||||||||