Main article: Boxing at the 2010 South American Games
The Men's 69 kg event at the 2010 South American Games had its quarterfinals held on March 22, the semifinals on March 24 and the final on March 27.
Medalists
| Gold | Silver | Bronze |
Brian Castaño Argentina
|
Leonard Carrillo Colombia
|
Esquiva Florentino BrazilJonny Sanchez  Venezuela
|
Results
| Quarterfinals | Semifinals | Final | |||||||||
| Leonard Carrillo (COL)
| 11 | ||||||||||
| Jonny Sanchez (VEN)
| 5 | ||||||||||
 Luis Mancilla (BOL)
| |||||||||||
| Jonny Sanchez (VEN)
| RSC | ||||||||||
| Leonard Carrillo (COL)
| 1 | ||||||||||
| Brian Castaño (ARG)
| 7 | ||||||||||
| Esquiva Florentino (BRA)
| RSC | ||||||||||
 Gabriel Castillo (PAN)
| |||||||||||
| Esquiva Florentino (BRA)
| 6 | ||||||||||
| Brian Castaño (ARG)
| 9 | ||||||||||
| Brian Castaño (ARG)
| 12 | ||||||||||
 Marco Quiroz Orellana (ECU)
| 1 | ||||||||||