Misplaced Pages

Brensocatib

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Chemical compound

Pharmaceutical compound
Brensocatib
Clinical data
Other namesAZD7986; INS1007
Identifiers
IUPAC name
  • (2S)-N-ethyl]-1,4-oxazepane-2-carboxamide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC23H24N4O4
Molar mass420.469 g·mol
3D model (JSmol)
SMILES
  • CN1C2=C(C=CC(=C2)C3=CC=C(C=C3)C(C#N)NC(=O)4CNCCCO4)OC1=O
InChI
  • InChI=1S/C23H24N4O4/c1-27-19-12-17(7-8-20(19)31-23(27)29)16-5-3-15(4-6-16)11-18(13-24)26-22(28)21-14-25-9-2-10-30-21/h3-8,12,18,21,25H,2,9-11,14H2,1H3,(H,26,28)/t18-,21-/m0/s1
  • Key:AEXFXNFMSAAELR-RXVVDRJESA-N

Brensocatib is an investigational new drug that is being evaluated to treat bronchiectasis. It is a dipeptidyl-peptidase I (also known as cathepsin C) inhibitor.

References

  1. "Brensocatib - Insmed". AdisInsight. Springer Nature Switzerland AG.
  2. Chalmers JD, Usansky H, Rubino CM, Teper A, Fernandez C, Zou J, et al. (October 2022). "Pharmacokinetic/Pharmacodynamic Evaluation of the Dipeptidyl Peptidase 1 Inhibitor Brensocatib for Non-cystic Fibrosis Bronchiectasis". Clinical Pharmacokinetics. 61 (10): 1457–1469. doi:10.1007/s40262-022-01147-w. PMC 9553789. PMID 35976570.
Stub icon

This pharmacology-related article is a stub. You can help Misplaced Pages by expanding it.

Categories: