Brian McLaughlin may refer to:
- Brian McLaughlin (footballer born 1954) (1954–2009), Scottish footballer and coach
- Brian McLaughlin (footballer born 1974), former footballer
- Brian McLaughlin (Gaelic footballer), Irish sportsperson who represented Donegal
- Brian J. McLaughlin (born ca. 1957), former Boston City Council member
- Brian M. McLaughlin (born 1952), former American Democratic politician from Flushing, Queens
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