Brian Nelson may refer to:
- Brian Nelson (screenwriter) (born 1964), American screenwriter and producer
- Brian Nelson (Northern Irish loyalist) (1947–2003), chief of intelligence for the Ulster Defence Association
- Brian Nelson (literature professor) (born 1946), literature professor, author and translator of French literature
- Brian E. Nelson, lawyer and government official
See also
- Bryan Nelson (born 1958), member of the Florida House of Representatives
- Bryan Nelson (ornithologist) (1932–2015), British ornithologist and academic
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