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Brian Worthington FRS FRCR (9 June 1938 – 9 December 2007) was the first radiologist to be elected a Fellow of the Royal Society and is acknowledged as a pioneer in clinical magnetic resonance imaging. He was born in Oldham, England and was educated at Hulme Grammar School, training at Guy's Hospital after graduating in physiology and medicine. After graduation his career developed rapidly, particularly in the field of MRI research and he was subsequently admitted as a Fellow of the Royal College of Radiologists.

Early career

From grammar school he won a scholarship to Guy's Hospital, where he won three major prizes in medicine and graduated with MB BS in medicine and BSc (Hons) in physiology. After his medical training, he worked at Guy's Hospital and then moved from London and worked as a consultant radiologist in Nottingham and Derby hospitals and from 1971 as a consultant neuroradiologist. He was part of the developing medical school in the then recently built Queen's Medical Centre (QMC) teaching hospital Nottingham, and formed a close working relationship with Rex Coupland who was Foundation Professor in the University of Nottingham Department of Human Morphology. In 1975, he was appointed as a Reader in the Department of Human Morphology and in 1981 as Professor of Diagnostic Radiology.

MRI development

Although primarily a neuroradiologist, he was also interested in neuroimaging of the brain and when the University of Nottingham became a centre of early MRI development, it quickly became apparent that there was a need for accurate correlation of magnetic resonance images with anatomical structures and Worthington was considered to be the local expert. Raymond Andrew's research group had published small novel cross sectional images of fruit and also a human wrist in the scientific journal Nature and it was with this group that he made his first clinical evaluations in Nuclear Magnetic Resonance Imaging. When the research group scaled up to whole body imaging experiments, he was instrumental in the first evaluation study to be carried out on a series of patients with a variety of intracranial abnormalities.

Following the disbandment of Andrew's group, he began a long collaboration and association with Peter Mansfield and eventually held the post of Professor of Diagnostic Radiology at the University of Nottingham and had his own small department in the QMC. In Mansfield's group he contributed to the potential of Echo-planar imaging, attending and promoting this technique at conferences and meetings around the world. He lectured on clinical aspects of MRI and gave more than 300 invited lectures at international events and produced over 300 scientific and clinical papers. As well as producing seminal clinical evaluation papers, he contributed to a whole range of clinical applications such as obstetrics and gynaecology which included physiological and pathological studies in pregnancy. He trained a large number of clinical radiologists, who went on to develop the clinical applications of MRI.

Throughout his career his papers related to MRI, X-ray and CT (computed tomography) scanning, as well as medical imaging in general. As a radiologist he was interested in all forms of medical imaging and much of his work has been archived as part of the Manuscripts and Special Collections catalogue by the University of Nottingham.

Personal life

Worthington was married with two sons. He had a great interest in the Icelandic language which he could speak quite well and when he retired, he took a part-time degree on the topic.

Honours

During the course of his life, he received many awards.

• He was elected President of the British Institute of Radiology in 1988 and in 1990 was awarded the Gold Medal of the Society of Magnetic Resonance.
• In 1998 he was elected Fellow of The Royal Society, the first radiologist to be admitted in its history and awarded the coveted Royal College of Radiologists Gold Medal for significant contribution in his field.

Death

He became ill from pancreatic cancer and died in December 2007.

References

1. ^ "Gold Medal". Royal College of Radiologists. Retrieved January 19, 2021.
2. "The Radiological Society of North America Names Honorary Members". RSNA. Retrieved January 18, 2021.
3. ^ Mansfield, Sir Peter; Roebuck, Eric J. (2013). "Brian Stewart Worthington. 9 June 1938 — 9 December 2007". Biographical Memoirs of Fellows of the Royal Society. 59: 423–435. doi:10.1098/rsbm.2013.0017. ISSN 0080-4606.
4. Beck, Felix (2008). "Professor Rex Ernest Coupland 1923-2008". Journal of Anatomy. 213 (6): 631–632. doi:10.1111/j.1469-7580.2008.01023.x. ISSN 0021-8782. PMC 2666132.
5. "A Brief History of Magnetic Resonance at Nottingham". Retrieved January 18, 2021.
6. Hinshaw WS, Andrew ER, Bottomley PA, Holland GN, Moore WS (April 1978). "Display of cross sectional anatomy by nuclear magnetic resonance imaging". The British Journal of Radiology. 51 (604): 273–80. doi:10.1259/0007-1285-51-604-273. PMID 647183.
7. Mansfield, Peter (3 January 2013). The Long Road to Stockholm. Oxford University Press. p. 219. ISBN 978-0-19-966454-2.
8. Bydder GM (December 2011). "Review. The Agfa Mayneord lecture: MRI of short and ultrashort T₂ and T₂* components of tissues, fluids and materials using clinical systems". The British Journal of Radiology. 84 (1008): 1067–82. doi:10.1259/bjr/74368403. PMC 3473831. PMID 22101579.
9. Hawkes RC, Holland GN, Moore WS, Worthington BS (October 1980). "Nuclear magnetic resonance (NMR) tomography of the brain: a preliminary clinical assessment with demonstration of pathology". Journal of Computer Assisted Tomography. 4 (5): 577–86. doi:10.1097/00004728-198010000-00001. PMID 6967878. S2CID 672587.
10. Powell MC, Symonds EM, Worthington BS (June 1986). "The application of magnetic resonance imaging to gynaecology". British Journal of Hospital Medicine. 35 (6): 393–403. PMID 3719207.
11. Dorrington, Mark (December 18, 2018). "The MRI story in Nottingham – a unique archive in the making". University of Nottingham. Retrieved January 18, 2021.
12. "Papers of Professor Brian Worthington; 1930s-2013". Jisc. Retrieved January 18, 2021.

• 1938 births
• 2007 deaths
• People educated at Oldham Hulme Grammar School
• Fellows of the Royal Society
• Fellows of the Royal College of Radiologists
• History of medical imaging
• People from Oldham