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Bryan J. Traynor is a neurologist and a senior investigator at the National Institute on Aging, and an adjunct professor at Johns Hopkins University. Dr. Traynor studies the genetics of human neurological conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). He led the international consortium that identified pathogenic repeat expansions in the C9orf72 gene as a common cause of ALS and FTD. Dr. Traynor also led efforts that identified other Mendelian genes responsible for familial ALS and dementia, including VCP, MATR3, KIF5A, HTT, and SPTLC1.

Dr. Traynor is a co-recipient of the Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases for the discovery of the C9orf72 repeat expansions, and the Sheila Essay Award for his contributions to our understanding of ALS. He also received the NIH Director’s Award.

Education

Dr. Traynor received his medical degree (MB, BCh, BAO, 1993), his Medical Doctorate (MD, 2000), and his Doctor of Philosophy (PhD, 2012) from University College Dublin. He also received his Master of Medical Science (MMSc) in drug development and clinical trial design from Harvard-MIT HST in 2004. He completed his neurology residency and fellowship at Brigham and Women’s Hospital and Massachusetts General Hospital.

Awards, prizes, and honors

• 2011 National Institute on Aging Director's Award
• 2012 Derek Denny-Brown Award
• 2012 Elected fellow of the American Neurological Association
• 2012 National Institutes of Health Director's Award
• 2013 Diamond Award
• 2013 Sheila Essey Award
• 2016 Potamkin Prize
• 2018 Health and Life Sciences 50 Honoree
• 2020 Elected fellow of the Royal College of Physicians of Ireland
• 2021 Elected fellow of the Royal College of Physicians (London)
• 2022 Elected member of the Association of American Physicians

Notable professional service

• Chief, Neuromuscular Diseases Research Section, NIA, NIH
• Team leader, RNA Therapeutics Laboratory, NCATS, NIH
• Member, Health Genetics of Health and Disease NIH Study Section (2015-2021)
• Chair, Congressionally Mandated Department of Defense ALS Research Program (2015-2019)
• Co-chair, NIH Gene Therapy Task Force
• Member, Scientific Program Advisory Committee, American Neurological Association
• Editorial board member, Journal of Neurology, Neurosurgery and Psychiatry; Neurobiology of Aging; JAMA Neurology (2017-2021); Lancet eClinicalMedicine.
• Associate editor, Brain

References

1. "Neuromuscular Diseases Research Section". National Institute on Aging. Retrieved 2019-03-26.
2. Renton, Alan E.; Majounie, Elisa; Waite, Adrian; Simón-Sánchez, Javier; Rollinson, Sara; Gibbs, J. Raphael; Schymick, Jennifer C.; Laaksovirta, Hannu; van Swieten, John C.; Myllykangas, Liisa; Kalimo, Hannu; Paetau, Anders; Abramzon, Yevgeniya; Remes, Anne M.; Kaganovich, Alice; Scholz, Sonja W.; Duckworth, Jamie; Ding, Jinhui; Harmer, Daniel W.; Hernandez, Dena G.; Johnson, Janel O.; Mok, Kin; Ryten, Mina; Trabzuni, Danyah; Guerreiro, Rita J.; Orrell, Richard W.; Neal, James; Murray, Alex; Pearson, Justin; Jansen, Iris E.; Sondervan, David; Seelaar, Harro; Blake, Derek; Young, Kate; Halliwell, Nicola; Callister, Janis Bennion; Toulson, Greg; Richardson, Anna; Gerhard, Alex; Snowden, Julie; Mann, David; Neary, David; Nalls, Michael A.; Peuralinna, Terhi; Jansson, Lilja; Isoviita, Veli-Matti; Kaivorinne, Anna-Lotta; Hölttä-Vuori, Maarit; Ikonen, Elina; Sulkava, Raimo; Benatar, Michael; Wuu, Joanne; Chiò, Adriano; Restagno, Gabriella; Borghero, Giuseppe; Sabatelli, Mario; Heckerman, David; Rogaeva, Ekaterina; Zinman, Lorne; Rothstein, Jeffrey D.; Sendtner, Michael; Drepper, Carsten; Eichler, Evan E.; Alkan, Can; Abdullaev, Ziedulla; Pack, Svetlana D.; Dutra, Amalia; Pak, Evgenia; Hardy, John; Singleton, Andrew; Williams, Nigel M.; Heutink, Peter; Pickering-Brown, Stuart; Morris, Huw R.; Tienari, Pentti J.; Traynor, Bryan J. (2011). "A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD". Neuron. 72 (2): 257–268. doi:10.1016/j.neuron.2011.09.010. ISSN 0896-6273. PMC 3200438. PMID 21944779.
3. Johnson, Janel O.; Mandrioli, Jessica; Benatar, Michael; Abramzon, Yevgeniya; Van Deerlin, Vivianna M.; Trojanowski, John Q.; Gibbs, J. Raphael; Brunetti, Maura; Gronka, Susan; Wuu, Joanne; Ding, Jinhui; McCluskey, Leo; Martinez-Lage, Maria; Falcone, Dana; Hernandez, Dena G.; Arepalli, Sampath; Chong, Sean; Schymick, Jennifer C.; Rothstein, Jeffrey; Landi, Francesco; Wang, Yong-Dong; Calvo, Andrea; Mora, Gabriele; Sabatelli, Mario; Monsurrò, Maria Rosaria; Battistini, Stefania; Salvi, Fabrizio; Spataro, Rossella; Sola, Patrizia; Borghero, Giuseppe; Galassi, Giuliana; Scholz, Sonja W.; Taylor, J. Paul; Restagno, Gabriella; Chiò, Adriano; Traynor, Bryan J. (2010). "Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS". Neuron. 68 (5): 857–864. doi:10.1016/j.neuron.2010.11.036. ISSN 0896-6273. PMC 3032425. PMID 21145000.
4. Johnson, Janel O; Pioro, Erik P; Boehringer, Ashley; Chia, Ruth; Feit, Howard; Renton, Alan E; Pliner, Hannah A; Abramzon, Yevgeniya; Marangi, Giuseppe; Winborn, Brett J; Gibbs, J Raphael; Nalls, Michael A; Morgan, Sarah; Shoai, Maryam; Hardy, John; Pittman, Alan; Orrell, Richard W; Malaspina, Andrea; Sidle, Katie C; Fratta, Pietro; Harms, Matthew B; Baloh, Robert H; Pestronk, Alan; Weihl, Conrad C; Rogaeva, Ekaterina; Zinman, Lorne; Drory, Vivian E; Borghero, Giuseppe; Mora, Gabriele; Calvo, Andrea; Rothstein, Jeffrey D; Drepper, Carsten; Sendtner, Michael; Singleton, Andrew B; Taylor, J Paul; Cookson, Mark R; Restagno, Gabriella; Sabatelli, Mario; Bowser, Robert; Chiò, Adriano; Traynor, Bryan J (2014). "Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis". Nature Neuroscience. 17 (5): 664–666. doi:10.1038/nn.3688. ISSN 1097-6256. PMC 4000579. PMID 24686783.
5. Nicolas, Aude; Kenna, Kevin P.; Renton, Alan E.; Ticozzi, Nicola; Faghri, Faraz; Chia, Ruth; Dominov, Janice A.; Kenna, Brendan J.; Nalls, Mike A.; Keagle, Pamela; Rivera, Alberto M. (2018). "Genome-wide Analyses Identify KIF5A as a Novel ALS Gene". Neuron. 97 (6): 1268–1283.e6. doi:10.1016/j.neuron.2018.02.027. ISSN 1097-4199. PMC 5867896. PMID 29566793.
6. Dewan, Ramita; Chia, Ruth; Ding, Jinhui; Hickman, Richard A.; Stein, Thor D.; Abramzon, Yevgeniya; Ahmed, Sarah; Sabir, Marya S.; Portley, Makayla K.; Tucci, Arianna; Ibáñez, Kristina (2021). "Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis". Neuron. 109 (3): 448–460.e4. doi:10.1016/j.neuron.2020.11.005. ISSN 1097-4199. PMC 7864894. PMID 33242422.
7. Johnson, Janel O.; Chia, Ruth; Miller, Danny E.; Li, Rachel; Kumaran, Ravindran; Abramzon, Yevgeniya; Alahmady, Nada; Renton, Alan E.; Topp, Simon D.; Gibbs, J. Raphael; Cookson, Mark R.; Sabir, Marya S.; Dalgard, Clifton L.; Troakes, Claire; Jones, Ashley R. (2021-10-01). "Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis". JAMA Neurology. 78 (10): 1236–1248. doi:10.1001/jamaneurol.2021.2598. ISSN 2168-6157. PMC 8406220. PMID 34459874.
8. "Derek Denny-Brown Neurological Scholar Award | American Neurological Association (ANA)". myana.org. Retrieved 2019-03-26.
9. "Wings Over Wall Street - Awards". wingsoverwallstreet.org. Retrieved 2019-03-26.
10. "ALS Association".
11. "American Academy of Neurology".
12. "Irish America Magazine". November 2018.
13. "Amyotrophic Lateral Sclerosis Research Program, Programmatic Panels; Congressionally Directed Medical Research Programs". cdmrp.army.mil. Retrieved 2019-03-26.

External links

• Bryan Traynor - Google Scholar

• 1969 births
• Living people
• Alumni of University College Dublin
• Harvard Medical School alumni
• Johns Hopkins University faculty
• National Institutes of Health