Misplaced Pages

Bufanolide

Names
IUPAC name 5ξ-Bufanolide
Systematic IUPAC name (5R)-5-phenanthren-1-yl]oxan-2-one
Identifiers
CAS Number	29565-35-3
3D model (JSmol)	Interactive image Interactive image
ChemSpider	102963
PubChem CID	115047
CompTox Dashboard (EPA)	DTXSID70276154
InChI InChI=1S/C24H38O2/c1-23-13-4-3-5-17(23)7-8-18-20-10-9-19(16-6-11-22(25)26-15-16)24(20,2)14-12-21(18)23/h16-21H,3-15H2,1-2H3/t16-,17?,18-,19+,20+,21-,23-,24+/m0/s1Key: PXOHOSHERMSUCD-YQMMVUDVSA-N
SMILES CC12CCCCC1CCC3C2CCC4(C3CCC4C5CCC(=O)OC5)C C12CC3(1CC24CCC(=O)OC4)CCC53(CCCC5)C
Properties
Chemical formula	C24H38O2
Molar mass	358.28718
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

Bufanolide is a C24 steroid and, indirectly, a parent structure of bufadienolide. Its derivatives was found in Bufo and Scilla, as an aglycone of cardiac glycosides and is usually toxic.

References

1. Tao Song, Yuanyuan Zhang, Qiongtao Song, Xue Han, Shengjiang Guan, Xuan Zhang, Xi Chu, Fenghua Zhang, Jianping Zhang, Li Chu (2017-08-16). "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K + currents expressed in HEK293 cells". Fundamental & Clinical Pharmacology. 31 (6): 695–700. doi:10.1111/fcp.12306. PMID 28755515. S2CID 1094461.{{cite journal}}: CS1 maint: multiple names: authors list (link)

• Bufanolides