C13 or C-13 may refer to:
- French Defence, Encyclopaedia of Chess Openings code
- C13 White Lead (Painting) Convention, 1921
- C13 grenade, the Canadian Forces designation for a M67 grenade
- Autovia C-13, a highway in Catalonia in Spain
- Caterpillar C13 Engine, an engine by Caterpillar Inc.
- HMS C13, a 1906 British C-class submarine
- IEC 60320 C13, a polarised, three pole plug used in electric power cables
- LNER Class C13, a 4-4-2T steam locomotive class of 1907, built for suburban passenger services around London
- OTO Melara C13
- Sauber C13, a 1994 racing car
- Caldwell 13 (NGC 457, the Owl Cluster or ET Cluster), an open star cluster in the constellation Cassiopeia
- The 13th century
- in music, a chord with the structure 1 - 3 - 5 - b7 - 9 - 13
- Carbon-13, a natural stable isotope of carbon
- Malignant neoplasm of hypopharynx ICD-10 code
- C13/C14 Coupler, a class of cable connector used by most desktop computers
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