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CD36 antigen

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Protein family
CD36 family
Identifiers
SymbolCD36
PfamPF01130
InterProIPR002159
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

CD36 antigen is a transmembrane, highly glycosylated, glycoprotein expressed by monocytes, macrophages, platelets, microvascular endothelial cells and adipose tissues. CD36 recognises oxidized low density lipoprotein, long chain fatty acids, anionic phospholipids, collagen types I, IV and V, thrombospondin and Plasmodium falciparum infected erythrocytes.

CD molecules are leucocyte antigens on cell surfaces. CD antigens nomenclature is updated at Protein Reviews On The Web (https://web.archive.org/web/20080920090434/http://mpr.nci.nih.gov/prow/).

Subfamilies

Human proteins containing this domain

CD36; SCARB1; SCARB2;

References

  1. Crombie R, Silverstein R (February 1998). "Lysosomal integral membrane protein II binds thrombospondin-1. Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif". The Journal of Biological Chemistry. 273 (9): 4855–63. doi:10.1074/jbc.273.9.4855. PMID 9478926.
This article incorporates text from the public domain Pfam and InterPro: IPR002159
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