Misplaced Pages

CUZD1
Identifiers
Aliases	CUZD1, ERG-1, UO-44, ERG1, ITMAP1, CUB and zona pellucida like domains 1
External IDs	OMIM: 616644; MGI: 1202881; HomoloGene: 7389; GeneCards: CUZD1; OMA:CUZD1 - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q26.13 Start 122,832,158 bp End 122,846,175 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 F3 Start 130,910,283 bp End 130,924,021 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas islet of Langerhans gonad testicle granulocyte stromal cell of endometrium mucosa of transverse colon spleen cerebellar hemisphere right hemisphere of cerebellum Top expressed in pyloric antrum islet of Langerhans embryo muscle of thigh embryo embryo duodenum triceps brachii muscle knee joint skeletal muscle tissue More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 50624 16433 Ensembl ENSG00000138161 ENSMUSG00000040205 UniProt Q86UP6 P70412 RefSeq (mRNA) NM_022034 NM_008411 RefSeq (protein) NP_071317 NP_032437 Location (UCSC) Chr 10: 122.83 – 122.85 Mb Chr 7: 130.91 – 130.92 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

CUB and zona pellucida-like domain-containing protein 1 is a protein that in humans is encoded by the CUZD1 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000138161 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000040205 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Chen D, Xu X, Zhu LJ, Angervo M, Li Q, Bagchi MK, Bagchi IC (Dec 1999). "Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1)". J Biol Chem. 274 (45): 32215–24. doi:10.1074/jbc.274.45.32215. PMID 10542259.
6. "Entrez Gene: CUZD1 CUB and zona pellucida-like domains 1".

External links

• Human CUZD1 genome location and CUZD1 gene details page in the UCSC Genome Browser.

Further reading

• Leong CT, Ong CK, Tay SK, Huynh H (2007). "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro". Oncogene. 26 (6): 870–80. doi:10.1038/sj.onc.1209836. PMID 16862170.
• Blanchetot C, Chagnon M, Dubé N, et al. (2005). "Substrate-trapping techniques in the identification of cellular PTP targets". Methods. 35 (1): 44–53. doi:10.1016/j.ymeth.2004.07.007. PMID 15588985.
• Leong CT, Ng CY, Ong CK, et al. (2004). "Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44". Oncogene. 23 (33): 5707–18. doi:10.1038/sj.onc.1207754. PMID 15184879.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Cayabyab FS, Tsui FW, Schlichter LC (2003). "Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1". J. Biol. Chem. 277 (50): 48130–8. doi:10.1074/jbc.M208448200. PMID 12361947.
• Huynh H, Ng CY, Lim KB, et al. (2001). "Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary". Endocrinology. 142 (7): 2985–95. doi:10.1210/endo.142.7.8247. PMID 11416020.

This protein-related article is a stub. You can help Misplaced Pages by expanding it.

• v
• t
• e

• Genes on human chromosome 10
• Protein stubs