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Cardamomin

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Cardamomin
Names
Preferred IUPAC name 2′,4′-Dihydroxy-6′-methoxychalcone
Other names (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.189.861 Edit this at Wikidata
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+Key: NYSZJNUIVUBQMM-BQYQJAHWSA-N
  • InChI=1/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+Key: NYSZJNUIVUBQMM-BQYQJAHWBN
SMILES
  • COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O
Properties
Chemical formula C16H14O4
Molar mass 270.27 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

Cardamomin (also known as cardamonin) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It has received growing attention from the scientific community due to the expectations toward its benefits to human health.

References

  1. Kimura, Y.; Takahashi, S.; Yoshida, I. (1968). "Studies on the constituents of Alpinia. XII. On the constituents of the seeds of Alpinia katsumadai hayata. I. The structure of cardamomin". Yakugaku Zasshi. 88 (2): 239–241. doi:10.1248/yakushi1947.88.2_239. PMID 5692492.
  2. Lee, J. -H.; Jung, H. S.; Giang, P. M.; Jin, X.; Lee, S.; Son, P. T.; Lee, D.; Hong, Y. S.; Lee, K.; Lee, J. J. (2005). "Blockade of Nuclear Factor- B Signaling Pathway and Anti-Inflammatory Activity of Cardamomin, a Chalcone Analog from Alpinia conchigera". Journal of Pharmacology and Experimental Therapeutics. 316 (1): 271–278. doi:10.1124/jpet.105.092486. PMID 16183703. S2CID 6069217.
  3. Gonçalves, Luís Moreira (2014). "An Overview on Cardamonin". Journal of Medicinal Food. 17 (6): 633–640. doi:10.1089/jmf.2013.0061. PMC 4060836. PMID 24433078.
Chalconoids and their glycosides
Chalconoids
Chalconoid glycosides
Acylated chalconoids
O-methylated chalconoids
Flavokavains
Synthetic


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