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Cationic amino acid transporter 4

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Protein found in humans
SLC7A4
Identifiers
AliasesSLC7A4, CAT-4, CAT4, HCAT3, VH, solute carrier family 7 member 4
External IDsOMIM: 603752; MGI: 2146512; HomoloGene: 20883; GeneCards: SLC7A4; OMA:SLC7A4 - orthologs
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)
Chromosome 22 (human)Genomic location for SLC7A4Genomic location for SLC7A4
Band22q11.21Start21,028,718 bp
End21,032,840 bp
Gene location (Mouse)
Chromosome 16 (mouse)
Chr.Chromosome 16 (mouse)
Chromosome 16 (mouse)Genomic location for SLC7A4Genomic location for SLC7A4
Band16|16 A3Start17,389,882 bp
End17,401,078 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right testis

  • left testis

  • prefrontal cortex

  • right hemisphere of cerebellum

  • right adrenal gland

  • right adrenal cortex

  • gonad

  • right frontal lobe

  • left adrenal cortex

  • Hypothalamus
Top expressed in
  • dentate gyrus of hippocampal formation granule cell

  • seminal vesicula

  • superior frontal gyrus

  • primary visual cortex

  • parotid gland

  • right ventricle

  • hippocampus proper

  • lacrimal gland

  • Region I of hippocampus proper

  • prefrontal cortex
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

6545

224022

Ensembl

ENSG00000099960

ENSMUSG00000022756

UniProt

O43246

Q8BLQ7

RefSeq (mRNA)

NM_004173

NM_144852
NM_001359891
NM_001359892
NM_001359893

RefSeq (protein)

NP_004164

NP_659101
NP_001346820
NP_001346821
NP_001346822

Location (UCSC)Chr 22: 21.03 – 21.03 MbChr 16: 17.39 – 17.4 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Cationic amino acid transporter 4 is a protein that in humans is encoded by the SLC7A4 gene.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000099960 – Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000022756 – Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Sperandeo MP, Borsani G, Incerti B, Zollo M, Rossi E, Zuffardi O, Castaldo P, Taglialatela M, Andria G, Sebastio G (Aug 1998). "The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome". Genomics. 49 (2): 230–6. doi:10.1006/geno.1998.5252. hdl:11566/82078. PMID 9598310.
  6. Hammermann R, Brunn G, Racke K (Oct 2001). "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4". Amino Acids. 21 (2): 211–9. doi:10.1007/s007260170029. PMID 11665818. S2CID 30892800.
  7. "Entrez Gene: SLC7A4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
By group
SLC1–10
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SLC11–20
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SLC21–30
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SLC31–40
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SLC41–48
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SLCO1–4
Ion pumps
Symporter, Cotransporter
Antiporter (exchanger)
see also solute carrier disorders


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