Centennial High School may refer to:
United States
- Centennial High School (Arizona), Peoria, Arizona
- Centennial High School (Compton, California), Compton, California
- Centennial High School (Corona, California), Corona, California
- Centennial High School (Bakersfield, California), Bakersfield, California
- Centennial High School (Pueblo, Colorado), Pueblo, Colorado
- Centennial High School (Roswell, Georgia), Roswell, Georgia
- Centennial High School (Idaho), Boise, Idaho
- Centennial High School (Champaign, Illinois), Champaign, Illinois
- Centennial High School (Howard County, Maryland), Ellicott City, Maryland
- Centennial High School (Minnesota), Blaine, Minnesota
- Centennial High School (Las Vegas), Las Vegas, Nevada
- Centennial High School (New Mexico), Las Cruces, New Mexico
- Centennial High School (Ohio), Columbus, Ohio
- Centennial High School (Oregon), Gresham, Oregon
- Centennial High School (Tennessee), Franklin, Tennessee
- Centennial High School (Burleson, Texas), Burleson, Texas
- Centennial High School (Frisco, Texas), Frisco, Texas
- Lakeview Centennial High School, Garland, Texas
- St. Lucie West Centennial High School, Port St. Lucie, Florida
Canada
- Centennial High School (Calgary), a senior high in Calgary, Alberta
- Centennial Regional High School, a multi-campus English language high school in Quebec
- Centennial Secondary School (Windsor, Ontario), also called Centennial High School, a former senior high school in Windsor, Ontario
See also
- Centennial Secondary School (disambiguation)
- Centennial Collegiate, Saskatoon, Saskatchewan, Canada, a high school