Champlain College is a private, coeducational college located in Burlington, Vermont, United States.
Champlain College may also refer to:
- Champlain Regional College, an English-language, publicly funded pre‑university college in Quebec, Canada
- Champlain College Saint-Lambert, Champlain Regional College campus serving the Greater Montreal Area
- Champlain College Lennoxville, Champlain Regional College campus serving the Eastern Townships
- Champlain College St. Lawrence, Champlain Regional College campus serving Quebec City
- Champlain College at Trent University in Peterborough, Ontario, Canada