Charlie, Charley or Charles Chase may refer to:
- Charles L. Chase (1828—after 1877), American politician from Minnesota
- Charles A. Chase (1864–1937), American tennis champion
- Charley Chase (1893–1940), American comedy actor, screenwriter and film director
- Charles Chase (boxer) (1931–1997), Canadian Olympic light middleweight
- Charlie Chase (broadcaster) (born 1952), American radio and television host (Crook & Chase)
- DJ Charlie Chase (born 1959), American DJ; key supporter of Puerto Rican music and culture
See also
- Charlie Hall Chase, English horse race established in 1969
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