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Chitin disaccharide deacetylase (EC 3.5.1.105, chitobiose amidohydolase, COD, chitin oligosaccharide deacetylase, chitin oligosaccharide amidohydolase) is an enzyme with systematic name 2-(acetylamino)-4-O-(2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucopyranose acetylhydrolase. This enzyme catalyses the following chemical reaction

2-(acetylamino)-4-O--2-deoxy-beta-D-glucopyranose + H₂O ${\displaystyle \rightleftharpoons }$ 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate

Chitin oligosaccharide deacetylase is present in Vibrio strains.

References

1. Kadokura K, Rokutani A, Yamamoto M, Ikegami T, Sugita H, Itoi S, Hakamata W, Oku T, Nishio T (May 2007). "Purification and characterization of Vibrio parahaemolyticus extracellular chitinase and chitin oligosaccharide deacetylase involved in the production of heterodisaccharide from chitin". Applied Microbiology and Biotechnology. 75 (2): 357–65. doi:10.1007/s00253-006-0831-6. PMID 17334758.
2. Hirano T, Kadokura K, Ikegami T, Shigeta Y, Kumaki Y, Hakamata W, Oku T, Nishio T (September 2009). "Heterodisaccharide 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine is a specific inducer of chitinolytic enzyme production in Vibrios harboring chitin oligosaccharide deacetylase genes". Glycobiology. 19 (9): 1046–53. doi:10.1093/glycob/cwp088. PMID 19553519.
3. Ohishi K, Yamagishi M, Ohta T, Motosugi M, Izumida H, Sano H, Adachi K, Miwa T (1997). "Purification and properties of two deacetylases produced by Vibrio alginolyticus H-8". Biosci. Biotechnol. Biochem. 61: 1113–1117. doi:10.1271/bbb.61.1113.
4. Ohishi K, Murase K, Ohta T, Etoh H (2000). "Cloning and sequencing of the deacetylase gene from Vibrio alginolyticus H-8". Journal of Bioscience and Bioengineering. 90 (5): 561–3. doi:10.1263/jbb.90.561. PMID 16232910.

External links

• Chitin+disaccharide+deacetylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

• Biology

• EC 3.5.1