Cholestenol Δ-isomerase | |||||||||
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Identifiers | |||||||||
EC no. | 5.3.3.5 | ||||||||
CAS no. | 37318-47-1 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a cholestenol Δ-isomerase (EC 5.3.3.5) is an enzyme that catalyzes the chemical reaction
- 5alpha-cholest-7-en-3beta-ol 5alpha-cholest-8-en-3beta-ol
Hence, this enzyme has one substrate, 5alpha-cholest-7-en-3beta-ol, and one product, 5alpha-cholest-8-en-3beta-ol.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is Delta7-cholestenol Delta7-Delta8-isomerase. This enzyme participates in biosynthesis of steroids.
See also
References
- Wilton DC, Rahimtula AD, Akhtar M (August 1969). "The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis". The Biochemical Journal. 114 (1): 71–73. doi:10.1042/bj1140071. PMC 1184797. PMID 5810070.
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