Cinquini is an Italian surname. Notable people with this surname include:
- Maria Cibrario Cinquini (1905–1992), Italian mathematician, married to Silvio
- Mattia Cinquini (born 1990), Italian footballer
- Mauro Cinquini [it] (born 1960), Italian field hockey player and coach
- Muzio Cinquini (died 1627), Italian Catholic bishop
- Oreste Cinquini (born 1947), Italian sporting director
- Renato Cinquini, Italian film editor
- Roberto Cinquini (1924–1965), Italian film editor
- Silvio Cinquini [it] (1906–1998), Italian mathematician, married to Maria
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