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Cladinose

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Cladinose
Names
IUPAC name (4R,5S,6S)-4-Methoxy-4,6-dimethyl-tetrahydropyran-2,5-diol
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C8H16O4/c1-5-7(10)8(2,11-3)4-6(9)12-5/h5-7,9-10H,4H2,1-3H3/t5-,6?,7-,8+/m0/s1Key: YHVUVJYEERGYNU-SBEGJHHSSA-N
  • InChI=1/C8H16O4/c1-5-7(10)8(2,11-3)4-6(9)12-5/h5-7,9-10H,4H2,1-3H3/t5-,6?,7-,8+/m0/s1Key: YHVUVJYEERGYNU-SBEGJHHSBA
SMILES
  • C1((CC(O1)O)(C)OC)O
Properties
Chemical formula C8H16O4
Molar mass 176.21 g/mol
Density 1.156 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒verify (what is  ?) Infobox references
Chemical compound

Cladinose is a hexose deoxy sugar that in several antibiotics (such as erythromycin) is attached to the macrolide ring.

In ketolides, a relatively new class of antibiotics, the cladinose is replaced with a keto group.

Erythromycin A with cladinose visible at bottom

External links


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