Colfosceril palmitate - Misplaced Pages

Pharmaceutical drug Pharmaceutical compound

Colfosceril palmitate
Clinical data

Trade names	Exosurf
Other names	phosphonato}oxy)ethyl]trimethylazanium
AHFS/Drugs.com	International Drug Names
ATC code	R07AA01 (WHO)
Identifiers
IUPAC name 2,3-di(hexadecanoyloxy)propyl 2-trimethylazaniumylethyl phosphate
CAS Number	63-89-8
PubChem CID	6138
ChemSpider	5908
UNII	319X2NFW0A
KEGG	D03585
ChEMBL	ChEMBL1200737
CompTox Dashboard (EPA)	DTXSID5046720
ECHA InfoCard	100.000.516
Chemical and physical data
Formula	C₄₀H₈₀NO₈P
Molar mass	734.053 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(OCC(OC(=O)CCCCCCCCCCCCCCC)COP()(=O)OCC(C)(C)C)CCCCCCCCCCCCCCC
InChI InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3 Key:KILNVBDSWZSGLL-UHFFFAOYSA-N
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Colfosceril palmitate (trade name Exosurf) is a drug used as a pulmonary surfactant. It is a drug that is used in surfactant deficient conditions such as infant respiratory distress syndrome in newborns.

References

Rubin BK (1996). "Therapeutic aerosols and airway secretions". Journal of Aerosol Medicine. 9 (1): 123–30. doi:10.1089/jam.1996.9.123. PMID 10160202.

v t e Other respiratory system products (R07)
Lung surfactants	Colfosceril palmitate Dipalmitoylphosphatidylcholine
Respiratory stimulants	Almitrine Amiphenazole Bemegride Dimefline Doxapram Etamivan GAL-021 Mepixanox Nikethamide Pentetrazol Prethcamide
5-HT4 receptor agonists	BIMU-8 Zacopride
Other agents for treating respiratory depression	Ivacaftor (+ lumacaftor, + tezacaftor, + elexacaftor/tezacaftor) Nitric oxide BW373U86 CX-546 CX-717

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