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Concentrative nucleoside transporter 1

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Protein found in humans
SLC28A1
Identifiers
AliasesSLC28A1, CNT1, HCNT1, Concentrative nucleoside transporter 1, solute carrier family 28 member 1, URCTU
External IDsOMIM: 606207; MGI: 3605073; HomoloGene: 37902; GeneCards: SLC28A1; OMA:SLC28A1 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)
Chromosome 15 (human)Genomic location for SLC28A1Genomic location for SLC28A1
Band15q25.3Start84,884,654 bp
End84,945,798 bp
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)
Chromosome 7 (mouse)Genomic location for SLC28A1Genomic location for SLC28A1
Band7|7 D3Start80,764,547 bp
End80,820,164 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lobe of liver

  • testicle

  • human kidney

  • duodenum

  • mucosa of ileum

  • jejunal mucosa

  • kidney tubule

  • muscle of thigh

  • apex of heart

  • renal medulla
Top expressed in
  • proximal tubule

  • duodenum

  • right kidney

  • human kidney

  • neck

  • pharynx

  • embryo

  • primary oocyte

  • bone marrow

  • secondary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9154

434203

Ensembl

ENSG00000156222

ENSMUSG00000025726

UniProt

O00337

E9PXX9

RefSeq (mRNA)
NM_001287761
NM_001287762
NM_004213
NM_201651
NM_001321721

NM_001321722

NM_001004184

RefSeq (protein)
NP_001274690
NP_001274691
NP_001308650
NP_001308651
NP_004204

NP_964014

NP_001004184

Location (UCSC)Chr 15: 84.88 – 84.95 MbChr 7: 80.76 – 80.82 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Concentrative nucleoside transporter 1 (CNT1) is a protein that in humans is encoded by the SLC28A1 gene.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000156222Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000025726Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ritzel MW, Yao SY, Huang MY, Elliott JF, Cass CE, Young JD (Apr 1997). "Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)". Am J Physiol. 272 (2 Pt 1): C707–14. doi:10.1152/ajpcell.1997.272.2.C707. PMID 9124315.
  6. "Entrez Gene: SLC28A1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1".

Further reading

Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
By group
SLC1–10
(1):
(2):
(3):
(4):
(5):
(6):
(7):
(8):
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
(24):
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
SLC41–48
(41):
(42):
(43):
(44):
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(46):
(47):
(48):
SLCO1–4
Ion pumps
Symporter, Cotransporter
Antiporter (exchanger)
see also solute carrier disorders
Purine receptor modulators
Receptor
(ligands)
P0 (adenine)
P1
(adenosine)
P2
(nucleotide)
P2X
(ATPTooltip Adenosine triphosphate)
P2Y
Transporter
(blockers)
CNTsTooltip Concentrative nucleoside transporters
ENTsTooltip Equilibrative nucleoside transporters
PMATTooltip Plasma membrane monoamine transporter
Enzyme
(inhibitors)
XOTooltip Xanthine oxidase
Others
Others
See also: Receptor/signaling modulators


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