Ctesiphon was a city in Mesopotamia that was intermittently the capital of the Arsacid and Sassanid Empires.
Ctesiphon may also refer to:
- Ctesiphon Arch, last remaining part of Ctesiphon city
- Ctesiphon of Vergium, a 1st-century missionary and the patron saint of Berja, Spain
- Ctesiphon (orator), an Athenian orator of the 4th century BCE
- Patriarchal Province of Seleucia-Ctesiphon, central ecclesiastical province of the Church of the East
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