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Cyclandelate

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Chemical compound
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Pharmaceutical compound
Cyclandelate
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Identifiers
IUPAC name
  • 3,3,5-trimethylcyclohexyl hydroxy(phenyl)acetate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.611 Edit this at Wikidata
Chemical and physical data
FormulaC17H24O3
Molar mass276.376 g·mol
3D model (JSmol)
Melting point55 to 56.5 °C (131.0 to 133.7 °F)
Boiling point192 to 194 °C (378 to 381 °F) (14 mmHg)
SMILES
  • O=C(OC1CC(CC(C1)(C)C)C)C(O)c2ccccc2
InChI
  • InChI=1S/C17H24O3/c1-12-9-14(11-17(2,3)10-12)20-16(19)15(18)13-7-5-4-6-8-13/h4-8,12,14-15,18H,9-11H2,1-3H3
  • Key:WZHCOOQXZCIUNC-UHFFFAOYSA-N
  (verify)

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.

References

  1. Smith AL (January 1965). "Cyclandelate (Cyclospasmol) in the Treatment of Peripheral Circulatory Diseases". Angiology. 16: 1–7. doi:10.1177/000331976501600101. PMID 14258038.
Peripheral vasodilators (C04)
Phenylethanolamine derivatives
Alpha blockers
Niacin and derivatives
Purine derivatives
Ergot alkaloids
Other peripheral vasodilators


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